Hands-on (Q)SAR (May 29 & 30, 2012)
Quantitative Structure Activity Relation (QSAR) models are more and more applied in various R&D domains, including but not limited to chemicals, pharmaceuticals, cosmetics, medical devices, food, crop protection agents, ... both for screening and regulatory purposes. For QSARs to be accepted by the regulatory authorities, issues such as applicability domain, uncertainty, validity and predictability
assessment have to be considered. These will be handled in more detail during the workshop. The aims of regulatory programs such as REACH include a high level of protection for both humans and the environment, facilitate the free movement of substances and increase the innovation of the industry. As a result of these objectives the development of alternative methods for the assessment of hazards of substances is stimulated in order to reduce animal testing.
QSAR models and software packages for physicochemical, environmental fate and (eco)toxicological parameters are presented from a theoretical and practical viewpoint, followed by exercises. Special attention will be paid to the integration and reporting of QSAR results.
In summary, aims of this workshop are to provide:
principles and background on the various methods;
tips & tricks how to use the QSARs;
attention points for the interpretation of results of QSARs;
composing QPRF and QMRF reports;
integration of QSAR data in registration files such as IUCLID.
For more information & registration: http://www.khk.be/QSAR